Mehdi Forozandeh Official Page

Fa

Associate Professor at the Faculty of Medical Sciences

Department of Medical Biotechnology (1999 - Present)

Ph.D. (1995)

Clinical Biochemistry

, Punjab, India
M.Sc. (1988)

Clinical Biochemistry

, Punjab, India
M.Sc. (1985)

chemistry

, Delhi, India
B.Sc. (1983)

chemistry

, Delhi, India

Genetic manipulation of breast cancer stem cells ( targeted exosomes to deliver miRNA and drug)
Biosensors

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Expert:

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Contact

foroz@modares.ac.ir
+98(21)82883861
+98(21)
pro.modares.ac.ir/~foroz
ISID

Curriculum Vitae (CV)

Publications

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Teaching

Current Teaching

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Teaching History

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People

2017

Darzi, Leila

Development of exosome as a CRISPR/Cas9 delivery system to introduce inducible suicide gene to TUBO-derived tumor in vivo
2019

Noroozi, Fatemeh

Targeted exosome production against dendritic cells DEC-205 receptor to deliver SARS-CoV-2 mRNA vaccine and assessment the immune responses in vivo
2021

Shoae, Mohammad

transferring CRISPR/Cas9 system by use of extracellular vesicles (exosome) as a nano-carrier to knock out the PLK1 gene in cell and mouse model of glioblastoma tumor (C6 cell line)

List of Graduates

M.Sc.
Ph.D.

2022

Samira, Narimani kohne shahri

Detection of exosomal miR/21 derived from serum of breast cancer patients usingmicrofluidic system
2022

Fatemeh, Afsharnoori

Production of Scfv recombinant antibody library against Lymphocyte functional associated antigene/1 using phage display
2020

Shima, Shabani

Production of recombinant SCfv library against glucose regulator protein 78 (GRP78) and appropriate antibody selection with ribosome display method
2018

Fatemeh, Jahanpeyma

Design and development of an enzyme.based nucleic acid lateral flow biosensor for E.coli ATCC 25922 detection
2015

Elaheh, Hashemi

Designing and constructing a biosensor (DNA ELISA) to detect E.coli ATCC 25922 using genomic DNA
2015

Fatemeh, Etezadi

Isolation and culture of blood derived EpCAM+ cells (CTC or MCF/7) using anti/EpCAM conjugated iron nanoparticle
2014

Etezadi, Fatemeh Zahra

Evaluation and verification of Lamp2b_HER2/specefic DARPin chimeric protein expression at the surface of exosomal nano particle/derived from Mesenchymal stem cell against HER2 antigen
2013

Sara, Noorani

Induction of cell death in breast cancer stem cell through microRNA mediated knockdown of STAT3 gene by lentiviral vector
2012

Shaghayegh, Anvari

Assessment of protective immunity of recombinant Accessory Cholera Enterotoxin (Ace) & Zonula Occludens Toxin (Zot) in mice
2012

Zahra Sadat, Hashemi

Investigation of TGF/Beta gene downregulation in UCB/derived HSCs on the 3D MBA scaffold to enhance their self renewal
2012

Atiyeh, Ghamnak

Investigation of miR/21 expression in human breast cancer stem cells
2012

Fatemeh, Salimi

microRNA mediated knockdown of CXCR1 gene by lentiviral vector to induce cell death in breast cancer stem cells
2012

Mona, Ardekanian

Development of a Sensitive Dipstick Test using Gold Nanoparticle/ Based DNA Biosensor for Detection of HCV, HBV
2011

Rouhollah, Valipour Nouroozi

Comparison of Giardia lamblia isolates from Tehran and Ahwaz cities by PCR and Sequencing
2011

Amin, Akbarian

Survey of genetic differences on Giardia lamblia in the Khorram abad city and surrounding villages using PCR and sequencing
2011

Mehrnoosh, Yazdanbakhsh

Inhibition of TPD52 gene expression with synthetic microRNA in MCF/7 breast cancer cell/line to decrease their growth and proliferation
2011

Sama, Shamloo

Genetic manipulation of cord hematopoietic stem cells by Zfx overexpression to enhance their self/renewality
2010

Maryam, Ahmadi

Production and optimization of rapid test for analyse of PSA gene expression with oligonucleotide conjugate gold nanoparticle as probe
2010

Fatemeh, Nematpour

Inhibition of WWP/1 oncogene expression by synthetic microRNA on cancer MCF/7 cell line
2009

Abdolvahab, Taghavi

Comparison of apoptosis, viability and maturation in mouse preantral follicle after slow freezing and cryotop vitrification
2009

Vahid, Jajarmi

CMA (Chimeric Primer / Mediated Amplification); A New Method For Isothermal Amplification
2009

Saeedeh, Askarian

Silencing steroid receptor RNA activator (SRA) gene by RNA interference (RNAi) technique and study it|s effect on progestron receptor (PR) gene in MCF7 cell line
2009

Lida, Langroud

Analysis of NANOG and Rex/1 suppression in Mesenchymal stem cells using RNA interference technique
2008

Roghayeh, Noroozi

Application of PCR/ELISA method whit RE gene for diagnosis of Toxoplasmosis in experimentaly infected rat (Rattus norvegicus)
2008

Mahdi, Paryan Noghani

Multiplex NASBA Real/Time for detection HIV/1 and HCV Viruses
2008

Vahid, Kia

Development of a Quantitative Multiplex Real/Time PCR for Simultaneous Detection of HBV and HTLV/I by Molecular Beacon Probes
2008

Maryam, Shahrabi Farahani

Designing and development of NASBA/ELISA technique for detection of Human immunodeficiency virus in blood samples
2007

Mohammad Ali, Owchi

The Effect of BMP4 on Differentiation of Embryonic Stem Cell to Erythroid Lineage in Serum Free Media
2006

Vahid, Khoddami Vishteh

Designing and construction of a silencer Vector Based on RNA Point promoter (H1) for development of stable RNA interference (RNAi) technique in mammalian cell systems
2006

Reihaneh, Ramezani

Designing and development NASBA/ELISA for detection of Mycobacterium tuberculosis EF/Tu mRNA
2005

Abbasali, Raz

Sex Determination of Single Blastomere by Real/time PCR for Prevention of Inherited Sex/Linked Disease
2005

Ali, Elmi

Evaluation of sensitivity and specificity of PCR/ELISA method for detection of helicobacter pylori and comparison the results of stool and gastric biopsy specimens.
2004

Majid, Nikpay

The analysis of Transmission Neomycin Resistance Gene into mouse zygote and it|s expression analysis
2004

Mohammad Reza, Dehghani

Cloning and expression of F protein gene (HR1 region) of NewCastle Disease Virus from NR43 isolate cDNA of Iran in E.coli
2003

Roshanak, Tahmasian

Cloning of HRI and HR2 Regions of F Protein Gene of Newcastle Disease Virus From NR43 Isolate of Iran
2003

Habib, Nasiri

Genetic typing of HLA DRB1.0101 A.0103 alleles by microliter plate/reverse hybridization assay (MRIL4) system
2001

Mahdi, Shamsara

Detection of Clostridium Botulinum Type A by PCR/ELISA Technique
2001

Shaban Ali, Khodashenas Limony

CCR5 Gene Amplification and Mutation Detection by Labeled Probe

2024-05-21

Mahboube, Shahrabi Farahani

Production of targeted exosomes against LFA/1 on T cells, to knock out PD/1 gene in them by CRISPR/Cas9 gene editing system
2024-02-20

Leila, Hossein pour madie

Production of targeted exosomes by specific SCFV for GRP78 antigen on U87MGcancer cell surface
2022-10-23

Mehdi, Tahmasbi

Development of two vertical (Flow/through) molecular diagnostic assay systems on the basis of gold nanoparticles (Au/NP) and enzymatic chemiluminescence for detecting HBV and comparing their sensitivities
2022-04-21

Batool, Mousavi koodehi

Investigation of Metformin hydrochloride drug effects in comparasion ,Metformin caprylic acid on miR/Iet7,miR/21 and miR/10b expression in MCF/7 and stem/like MDA/MB/231 breast cancer cell lines
2021-02-19

Mahlegha, Ghavami Nodeh

Generation and Characterization of Radiolabeled Targeted Exosomes for Breast Cancer HER2 Positive Cells Detection
2020-06-21

Yadegari Dehkordi, Sajedeh

Determining physical parameters of the Electro/magneto/chemotherapy Based on Induced Endocytosis in MCF/7 Breast Cancer Cells
2019-02-20

Fatemeh, Salimi

Selection of a specific scFv for HER2 by ribosome display and production of scFv directed exosomes
2018-08-23

Nazli, Jafarzadeh

Effects of K562 chronic myeloid leukemia cell line/derived exosomes on gene expression, immunological properties and redox potential of human bone marrow/derived mesenchymal stem cells and mouse macrophages
2018-06-22

Nahid, Shoaie shireh jini

Designing and constructing an electrochemical biosensor based on polyaniline film and gold nanoparticles to detect DNA bacteria E.coli ATCC 25922
2018-04-21

Amiri, Zohreh

The effects of various concentrations of free and dendrosomal nanoparticle salinomycin, doxorubicin and salinomycin with doxorubicin combination on expression of Let/7, miR/21, miR/10b, miR/128 in MCF/7 and MDA/MB/231 breast cancer cell lines
2018-09-23

Hosna, Gomari

Production of targeted Exosomal nanoparticles against Her2 from mesenchymal stem cell, for delivering doxorubicin to TUBO cell line and murine tumor model
2017-05-22

Delighan Kouhestani, Somayeh

Targeting specific miRNAs involved in breast cancer stem cells resistance to chemotherapeutic
2016-10-22

Mirzaqavami, Mehran

Determining of the spices and genotypes of Cryptosporidium spp. in rat, cat, pegion, and crow and survey their genetic relationship with human genotypes of Cryptosporidium in Tehran
2016-05-21

Shabanali, Khodashenas limony

Production and seperation of targeted Exosomal nanoparticles against Her2+breast cancer cells by engineering mouse denderitic cell intend to siRNA/miRNA delivery for TPD52 gene silencing
2016-02-20

Mehdi, Zolfaghari

Design a nanobiosensor based on DNA and gold nanoparticles for detection of active and viable but non culturable of listeria monocytogenes in rainbow trout (Oncorhynchus mykiss)
2015-01-21

Mohsen, Mirzaee

Study of small RNAs and biofilm genes expression and attachment in methicillin resistance and vancomycin intermediate Staphylococcus aureus isolates
2015-05-22

Alireza, Salimi Khorashad

Detection of Aspergillus species in clinical BAL sample from recipient organ patients by using Real/time TaqMan PCR and galactomanan assay and evaluation of glip &pksp gene expression after voriconazole treatment
2015-02-20

Samila, Farokhimanesh

Specific Inhibition of Metastasis Process in the Metastatic MDA/MB231 Cell Line Containing Cancer Stem Cells Using Mir/200 Family Target Sequence by Cooperation of Pleiotropically Acting BRMS1gene and Mir/31 in a Chimeric Construct
2014-08-23

Adel, Mohammadzadeh

Evaluation of AD/ MSC (Adipose derived Mesenchymal stem cells) as a vehicle for IFN/ Beta delivery in Experimental Autoimmune Encephalomyelitis
2014-02-20

Saeed, Daneshmandi

Denderitic Cell loading with tumor mRNA and specific mRNA of CD40 and ICOSL co/ stimulatory molecules and transfer of their gene using chitosan nanoparticles as tumor vaccine
2014-06-22

Masoud, Javanmardi

Investigation of Protective and Therapeutic Effects of Recombinant EGFR Mimotope Vaccine Displayed On Phage Nanoparticle Surface in Animal Models Treated By LL/2 Cell Line
2013-05-22

Hossein, Samadi Kafil

The effect of subinhibitory concentrations of Ampicillin, Vancomycin, Gentamicin and Ceftizoxime in expression of colonization genes of Enterococcus faecalis isolated from clinical samples on in vitro
2013-11-22

Gholamali, sabevarinejad

Genotyping of Neospora caninum using shedding oocyst from dogs and brain cyst from sparrows based on Nc5 gene and ITS1 region
2012-04-20

Farideh, Doctorzadeh

Evaluation of Immune Responses to Nanoparticles Conjugated to Cholera toxin B and N/terminal Domain of Pseudomonas aeruginosa Flagellin Fusion Protein in BALB/c Mice
2012-05-21

Mohsen, Arbabi

Morphological and Molecular Study of Dicrocoelium Dendriticum Isolates from Sheep and Goats Marker Using ITS2(rDNA)
2012-05-21

Fatemeh Maryam, Sheikholeslami

Genotyping of Pneumocyctis jirovecii in pulmonary infected patients and detection of frequency of polymorphisms associated with drug resistance in isolated strains from HIV+ patients in Tehran
2012-08-22

Roghayeh, Norouzi

Development of Real/ Time NASBA for detection and viability evaluation of Toxoplasma gondii in experimental toxoplasmosis in rat and its comparsion with Real/Time RT/PCR pre & post treatment with spiramycin
2012-10-22

Ebrahim, Badparva

Survey of Blastocystis Subtypes in Human, Cattle and Birds and Relative Genotypes between Them
2011-06-22

Fatemeh, Safari

The effect of myocardial ischemia reperfusion injury on transcription and expression of UCP2 and UCP3: the role of Renin/Angiotensin System
2011-08-23

Majid, Pirestani

Molecular characterization and genetical comparison Isolate of Entrocytozoon spp. and Encephalitozoon spp. from human (HIV+), calve, pigeon and free/ranging rats using ribosomal RNA gene
2011-12-22

Mahmoud, Mahami Oskouei

Molecular Characterization of Fasciola SPP. isolates from cattle and sheep using ITS (rDNA) region
2011-06-22

Gholamreza, Khamisipour

Generation of human hematopoietic lineage cells from induced fibroblasts by Adenovectors carrying embryonically active genes
2011-08-23

Mehdi, Allahbakhshian Farsani

Genetic manipulation of cord blood hematopoietic stem cells (HOXB4 over expression and TGF/ knockdown), for enhancement of self renewal of HSCs with differentiation potential to different blood cell lineages
2010-04-21

Shahnaz, Shirbazou

Designing and development of NASBA/ELISA for detection and quantify of Leishmania in Skin ulcer Sample Before and After Treatment by Glucantime
2010-08-23

Leila, Parvaneh

The effect of fatty acids (palmitate, oleate) on insulin resistance and gene expression, protein level and activity of protein tyrosine phosphatase 1 B (PTP1B) in muscle cell line C2C12
2009-02-19

Parvaneh, Nikpour

Studying stem cell self/renewal genes in bladder cancer and evaluation of interfering in their expression using RNAi technique
2009-04-21

Fatemeh, Peyghambari

Expression Pattern of Integrins and their Ligand (Osteopontin) in Mouse Endometrium After Estrogen and Progesterone Administration
2009-10-23

Zohreh, Makoolati

Male germ cell production from mouse embryonic stem cell following co/culture or treatment with BMP4 in vitro and transplantation to testis of adult mouse azoospermia model

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